Akhurst lab ucsf Christoph Kirst, Ph. She completed her residency in Internal Medicine at UCSF and is a ‪Cardiovascular Research Institute, UCSF‬ - ‪‪Cited by 20,351‬‬ - ‪TGFbeta signaling‬ - ‪Pulmonary disease‬ - ‪Vascular biology‬ - ‪Gene regulation‬ - ‪noncoding RNA‬ RJ Akhurst, A Hata. akhurst@ucsf. She has over 25 years of experience working with mouse models of cancer, focusing on the TGFβ UCSF Health. The Barcellos-Hoff laboratory studies breast cancer, mammary radiation carcinogenesis, and mechanisms to augment radiotherapy by 1) determining Lab Site Research; Training; Awards NI, Del Cid JS, Hann BC, Yang S, Giddabasappa A, Noorbehesht K, Yang B, Dal Porto J, Tsukui T, Niessen K, Atakilit A, Akhurst RJ, Sheppard D. We primarily study mice but are committed to applying the knowledge we gain Department of Anatomy and Program in Human Genetics, Rosemary J. Jennifer LaVail. PMID: 30832732 PMCID: PMC6399967 DOI: 10. edu. If a target Welcome to the Koliwad Lab at UCSF My laboratory investigates how innate immune cell types in tissues and organs throughout the body sense nutrients, and how this sensory capacity impacts metabolic function under normal conditions and contributes to common and devastating diseases, such as obesity, diabetes, atherosclerosis, and fatty liver Jenna Borovinsky joined UCSF's Osher Center for Integrative Health and the SEA Lab in March 2023. The Seligman Research Lab at UCSF's Center for Vulnerable Populations is committed to creating communities where healthy food is affordable and easily accessible by everyone. Browse by Cancer Type A long term goal of the lab is to understand how the measurable properties of tissues derive the individual properties of cells and their interactions. We also use phenotypic screening and in silico predictions to identify and decipher the mechanisms through which Thomson Lab Desai Lab Jun Lab El Samad Lab Thomson Lab Labarge Lab Schaffer Lab Craik Lab Klein Lab Tlsty Lab Vale Lab Huber Group Abate Lab We thank the following organizations for their generous support: Chan Zuckerberg Biohub National UCSF Chemistry and Chemical Biology Graduate Program (CCB) UCSF Tetrad graduate program. June 2014: Our imagenomics work won W. Mirzoeva OK, Akhurst RJ, Balmain A. The development of a complex organism from a fertilized egg, one of biology's most astonishing transformations, relies on intercellular communication. ; Miyazono, K. England, PhD Chemical Biology and Drug Development Laboratory Our research is focused on developing chemical tools for decoding biology and advancing medicine. The NIH has funded our growing collaboration with the Klein Lab to investigate the self-organizing properties of the intestinal mesenchyme. Join Facebook to connect with Farmext Lab Hòa Bình and others you may know. edu 415-514-9219 555 Mission Bay Blvd South Rm 452Q San Francisco CA 94143 FedEx only: use Ongoing Projects. ; Akhurst, R. We strive to share these jobs faithfully and equitably – and to acknowledge each other’s efforts. Outreach Zhao Lab advances drug development and regulatory science through cutting-edge research in pharmacometrics, drug delivery modeling, and artificial intelligence (AI)-based tools that will closely impact drug development and regulatory Photo Who Research interests Outside the lab Nadav Ahituv, PhD Professor nadav. TGF-b is required for normal In human patients, responses to checkpoint blockade therapy correlate with tumor mutation load, and intrinsic resistance associates with pre-treatment signatures of epithelial mesenchymal Rosemary AKHURST, Professor (Full) | Cited by 15,622 | of University of California, San Francisco, CA (UCSF) | Read 146 publications | Contact Rosemary AKHURST View Rosemary Akhurst’s profile on LinkedIn, a professional community of 1 billion members. The Kutys Lab at UCSF bridges engineering and cell biology to uncover mechanisms governing tissue architecture, morphogenesis, and disease. Stem Cell Reports. 1101/cshperspect. Elder DE, Bastian BC, During pregnancy, humans are exposed to thousands of chemicals. edu office: 415-502-6526 lab: 415-502-6510 Peter Zhong Lab Manager sheng. Our lab is located on the UCSF Parnassus Campus in the Ray and Dagmar Dolby Regenerative Medicine Building . Delrosario R, Khoroshkin M, Goodarzi H, Arnold TD, Niaudet C, Pang MF, Siegenthaler J, Gaengel K, Jung B, Ferrero GM, Mukouyama YS, Fuxe J, Akhurst R, Betsholtz C, Sheppard D, Reichardt LF Mesangial cell αvβ8-integrin Bridget attended Johns Hopkins for her M. We draw from various complementary modalities of data in order to paint a Living Tumor Biopsies to Interrogate Immune Function and Response to Therapy NIH R21CA196468 Sep 1, 2015 - Aug 31, 2018 Role: Principal Investigator: Manipulating collectivity and Niches for Developing CD8 Immunity NIH R01AI114787 Jun 15, 2015 - May 31, 2020 Role: Principal Investigator: CUTTING EDGE LINEAGE TRACKING OF TUMOR-EDUCATED Human Exposure Laboratory. Vis. Our group aims to define the ways in which the brain and immune system communicate during development, adulthood, and aging, and to harness these pathways to develop treatments for neuropsychiatric diseases including schizophrenia and neurodegeneration. gartner@ucsf. Clin Cancer Res. he moved to UCSF as Professor and Vice Chair of Research in the Department of Radiation Oncology. View in: He also co-directs the Parker Institute of Cancer Immunotherapy at UCSF and co-leads the Cancer Immunity and Immunotherapy Program in the Cancer Center. July 1, 2024 – June 30, 2029 - UCSF Specialized Programs of Research Excellence (SPORE) in Prostate Cancer $26 Million ‘Grand Challenge’ Project Will Probe Role of Inflammation in Cancer UC San Francisco Professor Thea Tlsty, PhD, is a winner of the “Grand Challenge” competition sponsored by Cancer Research UK (CRUK), an ambitious international funding initiative that aims to answer some of the biggest open questions in cancer. Helen Diller Family Comprehensive Cancer Center, University of California San Francisco; Director of UCSF HDFCCC Preclinical Therapeutics Research Summary: Dean Sheppard's laboratory studies how cells respond to and modify their surroundings using receptors called integrins. They are innate lymphocytes that use cell surface NK receptors to distinguish between self and non-self (or altered-self). Lab Pics! More. Facebook gives people the power to share and makes the world more We study how TGFβ regulates these processes in vivo, and how genetic variation affects TGFβ related diseases and drug outcomes. View in: PubMed Shu X, Wang L, Colip L, Kallio K, Remington SJ. Our research is divided into three main foci: Leveraging chemical proteomic technologies for the development of covalent Research in the Kornberg lab investigates cell-cell signaling processes that regulate and sculpt organogenesis and morphogenesis during development. December 10, 2024. TGFβ signaling is important in cancer, vascular, and stem cell biology, as well as tumor drug-resistance and immunotherapy. Gabby joins the lab. ALS and Frontotemporal Dementia (FTD) Single-nucleus sequencing reveals enriched expression of genetic risk factors in extratelencephalic neurons sensitive to degeneration in ALS Xiaokun Shu Lab; Bill Weiss Lab; Principal Investigator Su Guo, PhD, has expertise in molecular biology, genetics, cell biology, developmental biology, and neurobiology. Studying the Molecular Basis of Somatosensation UCSF Mail Code 2140 Genentech Hall Room N-272E 600 16th Street San Francisco, CA 94158-2140 The Barcellos-Hoff laboratory studies radiation carcinogenesis and biologically augmented radiotherapy. Weiss Lab at UCSF! We study neural and cancer stem cells during malignant progression. Nature Katsuno Y, Meyer DS, Zhang Z, Shokat KM, Akhurst RJ, Miyazono K, Derynck R. , MS: Research: Publications: Websites: Assistant Professor Email: [email protected] Phone: 415-502-7372 Address: UCSF Sandler Neurosciences Center Student Success at UCSF. kuang@ucsf. Akhurst’s research is focused on mouse developmental and cancer genetics, and the translation of findings to study of human vascular diseases and cancer. proteomics, metabolomics) routinely glean Professor and Principal Investigator zev. Kelly, PhD Mark J. 15. He completed a residency in dermatology at UCSF. View in: PubMed Mentions: 761 Fields: Dru Drug Therapy Pha Pharmacology. Cardiovascular Research Institute University of California, San Francisco Smith Cardiovascular Research Building Room 382 555 Mission Bay Blvd South San The Arkin Lab at UCSF provides the experimental data that is needed to optimize preclinical safety predictions. Robert Hamilton Jr. Lab Members. Aguilar Lab summer of 2024. We are particularly interested in tissue structure, a property of tissues that is essential to their function, yet oddly, is highly heterogeneous in most human organs. 47 UCSF Researchers Are Honored for Their High-Impact Science. Rosemary. edu: In The News. Publications Arteaga C, Warters R, Akhurst RJ, Barcellos-Hoff MH. edu tel: 415-514-4498 fax: 415-514-4507 Alyssa Lam Administrative Assistant Working with the Minor Lab at UCSF, we are using a combination of X-ray crystallography, protein engineering, and synthetic/medicinal chemistry to better understand the mechanism of known TREK modulators (e. 10. Murnane MM, Dhimolea DE, Li LR, Bariteau BM, Wheeler WD, Akhurst AR, Logan LA, Munster MP, Wiita WA, Martin Research Summary. Bouquet F, Pal A, Utilizing mice with global or conditional knockouts of the epithelial-restricted integrin, avß6, and the widely expressed integrins, a5ß1, a9ß1, avß5 and avß8, the lab has identified important My Lab Website: Profile at pharmchem. develop PRIME, a prime-editing-mediated high-throughput genetic screen method for single-base resolution analysis of genomic sequences. Carlos Corvera is chief of the Hepatobiliary & Pancreatic Surgery Program at UCSF Medical Center and a cancer surgeon at the UCSF Helen Diller Family Comprehensive Cancer Center. Jim Wells Harry Wm. Selected publications Biospecific chemistry for covalent linking of The Savic Lab aims to develop translational platforms able to predict drug exposure levels and efficacy in clinical studies and, thereby, to optimize dosing. PMID: 22028490 To achieve our goals, the laboratory works in close collaboration with physicians and laboratory investigators, and uses a wide variety of genome sequencing methods to study patient biopsy samples and preclinical models. While the study of these pathogens has advanced our The Munster lab is committed to the eradication of cancer. We are interested in the pancreatic beta cell – a cell whose relative or absolute deficiency results in either type 2 or type 1 diabetes mellitus. Open positions are listed on our She first joined the Gaw Lab in 2019 as a student in the UCSF/Kaiser Permanente Undergraduate Research Internship (URI) Program, where her project was "Characterization of Fc gamma receptors: IgG, how does it get from mom to baby?" She has continued to work in the Gaw Lab in projects related to COVID-19 in pregnancy and placental explants as ex Aguilar Lab @ UCSF. UCSF Profiles is managed by the UCSF Clinical and Translational Science Institute (CTSI), part of the Clinical and Translational Science Award program funded by the National Center for Advancing Translational Sciences (Grant Number UL1 TR000004) at the National Institutes of Health (NIH). Kelly Biosketch mark. edu tel: 415-476-1866 fax: 415-514-1028 Yiming (Kimmy) Kuang Lab Manager yiming. Studies done in San Francisco and at the University of California’s White Mountain Research His lab is translational in that he utilizes a spectrum of techniques and studies that span from mouse, large animal physiologic models, human tissue, human biomarkers and genetic approaches to understanding the disease. When I’m not working, I’m usually hanging out with The Desai Lab is located at the UC San Francisco Mission Bay campus in a contemporary research facility. 2016 Apr 5. Click on a faculty name to view a detailed description of an individual research program, contact information, The systems-level frameworks implemented in our lab ensure a truly unbiased and systematic approach to studying this key biological challenge. Hind Professor in Pharmaceutical Sciences and Professor in Molecular and Cellular Pharmacology jim. With a culture of collaboration, a commitment to excellence, and access to cutting-edge laboratory and clinical technologies, the UCSF cancer community works tirelessly to improve outcomes for cancer patients everywhere. Congratulations to Veronica for being selected as a UCSF Discovery Fellow. edu office: 415-476-1838 lab: 415-476-5166 fax: 415-514-4361 Peter Lu Administrative Analyst peter. Our lab uses small molecules and engineered proteins to address some of the most challenging problems in chemical biology and early-stage drug discovery. We focus on translational projects which have an ability to deliver real-world clinical impact. 2022 05 10 Central role of ShcA in differential TGF-beta signaling, epithelial plasticity and carcinoma cell behavior NIH R01CA198179 Apr 1, 2016 - Mar 31, 2021 Role: Principal Experience: UCSF · Location: Belvedere Tiburon · 346 connections on LinkedIn. The Goodarzi Lab combines modern experimental and computational technologies to understand complex human diseases at a molecular level. Neurosci Lett. Keck Foundation support. Using Intracellular bacterial pathogens as tools. Popular Searches. Search UCSF. Carroll EC, Yang H, Jones JG, Oehler A, Charvat AF, Montgomery KM, Yung A, Millbern Z, Vinueza NR, DeGrado WF, Mordes DA, Condello C, Gestwicki JE. Home Research People Publications News Gallery Contact Rosetta Our Wiki Lab members Tanja Kortemme My main scientific interests range from the details of the physical interactions between atoms and molecules to the architecture and evolution of interaction networks in complex biological systems. edu Associate Director Mark J. , Third Floor San Francisco, CA 94158 Phone: (415) 514-2629 Hours: M-F, 7 a. Nadav Ahituv, PhD Principal Investigator nadav. The disorders studied include Parkinson's disease, primary and secondary Affiliation. Jenna received her B. Sponsor: NIH, Sponsor Award ID: R01CA240984 Emeritus Faculty. Charles Ordahl. I started my post-doctoral training in the laboratory of Rosemary Akhurst, an Julius Lab at UCSF. For the best experience, try Chrome or Firefox. Success in graduate school requires care and attention to all aspects of your life: health and wellness, community, career development, personal and professional relationships, and security and safety. Our lab focuses on defining the © 2024 The Regents of the University of California 1. Go to UCSF Profiles, powered by July 1, 2019 - June 30, 2024 - An antisense RNA-mediated regulatory program that drives cancer metastasis , Principal Investigator . Contact Us; Laboratory for Visual Neuroscience Department of Ophthalmology Mission: To devise better ways to prevent and treat vision loss due to amblyopia and strabismus, and to advance medical science by understanding the human visual system. Stem-cell states Rosemary Akhurst is a professor in the HDF Comprehensive Cancer Center at UCSF. Chem Biol. elegans as an experimental system to investigate neural circuits that regulate feeding behavior, neuroendocrine regulators of fat metabolism, and how metabolic state regulates behavioral plasticity. Many of these chemicals are harmful to the mother and developing baby. edu Discovering gene regulatory elements in the human genome and linking mutations within them to specific phenotypes. PMID: 23000686; PMCID: PMC3520610. The lab members are a close-knit, friendly bunch from all over the world. Zheng, B. Akhurst is in the Cancer Research Institute, University of California – San Francisco, San Francisco, CA 94143-0875, USA rakhurst Working with the Minor Lab at UCSF, we are using a combination of X-ray crystallography, protein engineering, and synthetic/medicinal chemistry to better understand the mechanism of known TREK modulators (e. In addition to the focus area within BMS, a All of the faculty associated with the BMS graduate program are listed below. If you have further questions, are interested in future laboratory positions, or if you are a patient interested in participating in research, please e-mail [email protected]. The Aguilar Lab studies natural killer (NK) cells, which are critical members of our immune system tasked with protecting us from viral infections and cancers. Lab Member Log In. News. Gross, PhD jdgross@cgl. We are a part of the Cancer Immunotherapy Program (CIP) at the UCSF Helen Diller Family Comprehensive Cancer Center as well as the Parker Institute for Cancer Immunotherapy. 2023 May 10. Neyton LPA, Patel RK, Sarma A, UCSF COMET Consortium, Willmore A, Haller SC, Kangelaris KN, Eckalbar WL, Erle DJ, Krummel MF, Hendrickson CM, Woodruff PG, Langelier CR, Calfee CS, Fragiadakis GK Critical role of CD206+ macrophages in organizing anti-tumor immunity. Excessive vascular sprouting underlies cerebral hemorrhage in mice lacking Research in the Ahituv Lab focuses on understanding the role of regulatory sequences in biology and disease. Cancer Center members are UCSF-appointed researchers—laboratory scientists, clinical investigators, providers of patient care, epidemiologists, and sociobehavioral scientists—who span dozens of academic departments within the Schools of In pursuit of the program's scientific goal, Cancer Immunology & Immunotherapy Program members engage in research, education and training, and community engagement activities aligned under the following aims: (415) 353-7839 Clinic; (415) 514-9769 Lab. Their work is Each lab member is expected to be ethical, respectful, and understand how their actions can impact others. J. - 5:30 p. Finally, every lab member gets a say about new hires. UCSF Biomedical The PICT Program brings together basic, translational and clinical scientists in order to integrate cutting edge, multi-modality imaging into all aspects of patient care and cancer research. edu 415-502-8084 Bo Huang, PhD Professor and Principal Investigator bo. 8 UCSF Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA. December 5, 2024. Translation:Humans Animals Cells. Arnold TD, Niaudet C, Pang MF, Siegenthaler J, Gaengel K, Jung B, Ferrero GM, Mukouyama YS, Fuxe J, Akhurst R, Betsholtz C, Sheppard D, Reichardt LF IQGAP1-dependent scaffold suppresses RhoA and inhibits airway smooth muscle contraction. I am a dermatologist and dermatopathologistwith expertise in diagnosing and treating patients with cutaneous neoplasms. In this role, I interpret molecular genetic testing for the prenatal and postnatal diagnosis of TGFβ1 inhibition increases the radiosensitivity of breast cancer cells in vitro and promotes tumor control by radiation in vivo. Selected Publications: 1. CELL-Diff: Unified diffusion modeling for protein sequences and microscopy images D. Rosenblum is a member of the American Association of Immunologists, Society for Investigative Dermatology, American Academy of Dermatology and Federation of Clinical Immunology Societies. UCSF, San Francisco, CA, USA. Giddabasappa A, Noorbehesht K, Yang B, Dal Porto J, Tsukui T, Niessen K, Atakilit A, Akhurst RJ, Sheppard UCSF Profiles is managed by the UCSF Clinical and Translational Science Institute (CTSI), part of the Clinical and Translational Science Award program funded by the National Center for Advancing Translational Sciences (Grant Number UL1 TR000004) at the National Institutes of Health (NIH). View in: PubMed 96 The Tison Lab @ UCSF focuses on using machine learning and large-scale epidemiologic and clinical research methods to achieve goals in disease prevention, prediction and disease phenotyping. Our lab focuses on identifying molecular mechanisms mediating immune suppression and evasion in brain tumors, with the goal of developing novel immunotherapeutics for these diseases. Every lab member is also responsible for some form of lab upkeep. We apply a variety of approaches, including classical and molecular genetics, and histological techniques ranging from fluorescence microscopy to fine structure analysis with the electron microscope. The genetic events that promote neural tumorigenesis. UCSF, 2021; Elected Member, American Academy of Arts and Sciences, AAAS, 2018 Gaengel K, Jung B, Ferrero GM, Mukouyama YS, Fuxe J, Akhurst R, Betsholtz C, Sheppard D, Reichardt LF. Christine Lin Applications Programmer [email protected] The Lu Lab is located in the Helen Diller Research Building at the UCSF Mission Bay campus in the Department of Neurological Surgery. Methods for high throughput discovery of fluoroprobes that recognize tau fibril polymorphs. Exp. Rosemary Akhurst, PhD. 35 Medical Center Way San Francisco, CA 94143 Phone: (415) 514-2347 Located at the Parnassus Campus of the University of California San Francisco (UCSF) in the Department of Laboratory Medicine, our lab focuses on reproductive immunology and the many questions that persist in the field of pregnancy biology, immunological or otherwise. Chronic TGF-β exposure drives stabilized EMT, tumor stemness, and cancer drug resistance with vulnerability In my clinical work, I am Assistant Director of the UCSF Clinical Cytogenetics laboratory. Contact Us. 618585 (2024). We are predominantly focused on metastatic progression in multiple cancers and Research laboratory of Jim Wells, PhD We are keenly focused on how cells remodel their extracellular proteome in health and disease. RESEARCH . M. Our laboratory leverages chemical biology and proteomic techniques to elucidate important mechanisms in innate immunity and to optimize drug discovery. in Molecular Biology from Colgate University and aims to pursue medical school in the future. Phenotypic reversion or death of cancer cells by altering signaling About UCSF. To date, we have described Lab Services at UCSF provides the full array of specialized diagnostic tests, both on-site in our hospitals and at convenient community locations. Multiplex, single-cell CRISPRa screening for cell type specific regulatory Translational research at the interface of chemical biology and nuclear medicine The scientific premise of the Evans lab is that there are natural, and largely untapped synergies between chemical biology and nuclear medicine. UCSF’s innovative, collaborative approach to patient care, research and education spans disciplines across the life sciences, making it a world leader in scientific discovery and its translation to improving health. The UCSF Medical Center is made up of three medical centers, at the Parnassus, Mount Zion and Mission Bay campuses. This method will be based on molecular dynamics (MD), a computational method that Dr. Studying the Molecular Basis of Somatosensation UCSF Mail Code 2140 Genentech Hall Room N-272E 600 16th Street San Francisco, CA 94158-2140 Jim Wells Harry Wm. Uma Mahadevan on Twitter. Gene networks reveal stem-cell state convergence during preneoplasia and progression to malignancy in multistage skin carcinogenesis. 2019. Zhang Lab @ UC Berkeley K. edu tel: 415-514-1017 UCSF Rock Hall Box 2911 1550 Working with the Minor Lab at UCSF, we are using a combination of X-ray crystallography, protein engineering, and synthetic/medicinal chemistry to better understand the mechanism of known TREK modulators (e. Patricia Calarco. The SARS-CoV-2 receptor ACE2 is expressed in mouse pericytes but not endothelial cells: Implications for COVID-19 vascular research. 2011 Nov 01; 17(21):6754-65. For instance, molecular profiling technologies developed, refined, and applied by chemical biologists (e. Our lab studies fundamental mechanisms of mammalian morphogenesis across sub-cellular, cellular, tissue, and organismal On the cover: In this issue of Molecular Cell, Ren et al. UCSF Health. This includes preclinical investigation of Rosemary Akhurst, PhD studies the role of signaling molecules and genetic modifiers in vasculogenesis, the formation of the vascular network during development. UCSF Profiles is managed by the UCSF Clinical and Translational Science Institute (CTSI), KORTEMME LAB @ UCSF. Akhurst RJ, Arron ST, Boggs JME Meet some of UCSF's Women in Basic Science. Using PRIME, the authors identify essential nucleotides for enhancer activity and disease-associated functional genetic variants. At its core, this technique provides a quantitatively precise means of combining any combination of cells together into a small 4/2019 - Acknowledging and Negotiating the Mentee-Mentor Tensions Inherent in the Research Lab 4/2019 - Sharpening your Mentoring Skills (SyMS) with Sharon Milgram 6/2020 - Your Role in Workplace Diversity 10/2020 - DEI Champion Training © 2024 The Regents of the University of California Blood draw sites for all UCSF patients (those with cancer or other conditions) Blood Draw Lab at Mission Bay Pediatric and adult patients Ron Conway Family Gateway Medical Building 1825 Fourth St. At the SEA Lab, Jenna is a Clinical Research Coordinator for the HEAT BED Study and also assists with Dr. Harrison has been chosen as a UCSF Discovery Fellow. She believes that curiosity and a collaborative attitude are key to successful scientific inquiries. (closed UC holidays) Blood Draw Lab at Parnassus 400 Our research focuses on the mechanobiologic pathways controlling stem cell and skeletal cell differentiation in bone and cartilage. bioRxiv. With drug-induced liver injury (DILI) as one of the leading causes of attrition during drug development, we focus on building a computational platform that can accurately measure and predict DILI at the organismal and population levels. Critical Care/Lung Injury. Skip to Main Content. Learn more. Iain is awarded a UC President’s Postdoctoral Fellowship. Home Team The Kutys Lab resides within the Department of Cell and Tissue Biology at the University of California San Francisco Parnassus Campus. 1186/s40425-018-0493-9 Abstract We genetically encode unnatural amino acids in live cells and organisms to investigate biological processes in their natural settings and to develop new biotherapeutics. ha@ucsf. OVERVIEW. Iain joins the lab. A. Juggling, We are excited to meet UCSF graduate and PharmD students! Please reach out if you are interested in joining the Apsel Winger Lab! The Apsel Winger lab uses experimental methods to expand our understanding of the function of mutant kinases with the overall goal of improving targeted kinase therapies in vascular anomalies and cancer. Cancer research is conducted at UCSF across campuses, spanning many departments, programs, and specialties. 2009 Mar 27; 16(3):323-36. 2016, S0304 Mapping the circuitry of the pancreatic beta cell. Akhurst Lab. 2023 Mar 3:(193). Chardon FM, McDiarmid TA, Page NF, Daza RM, Martin BK, Domcke S, Regalado SG, Lalanne JB, Calderon D, Li X, Starita LM, Sanders SJ, Ahituv N, Shendure J. Our lab uses small molecules to better understand the biology of disease and to develop novel therapies. 2016, S0304 Joining UCSF. YAP charge patterning mediates signal integration through transcriptional Because James Wells is a common name, his publications are also manually curated in PubMed: James Wells, PhD, on PubMed 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 Lin Z, In my clinical work, I am Assistant Director of the UCSF Clinical Cytogenetics laboratory. He is a physician Rosemary Akhurst, PhD studies the role of signaling molecules and genetic modifiers in vasculogenesis, the formation of the Brian Shy, MD, PhD directs GMP manufacturing efforts for cell and gene therapies at UCSF. ucsf. BEGIN:VCALENDAR VERSION:2. (2023) Methods For Visualizing Intracellular Organelles. edu 415-514-9962 Office: GH-N512E About me. Dissecting medulloblastoma metastases from mouse spinal cord. KUTYS LAB @ UCSF. Experience: UCSF · Location: Belvedere Tiburon · 346 connections on LinkedIn. 0 CALSCALE:GREGORIAN PRODID:iCalendar-Ruby BEGIN:VEVENT CATEGORIES:Research & Academia DESCRIPTION:Presenter: James Heiserman\, Akhurst Lab\n\nTalk Title: TBD\n\n The Helen Diller Family Comprehensive Cancer Center has reinstated its Dill er Building Journal Club (JC) and Research-in-Progress (RIP) Zev Gartner, PhD Principal Investigator zev. doi: 10. How This Cancer Drug Could Make Radiation a Slam Dunk Therapy. m. ahituv@ucsf. Looks like you’re visiting UCSF Health on Internet Explorer. We primarily use C. My research focuses on the pathogenesis of cutaneous squamous cell carcinoma. Prostate Cancer Dream Team Gets $10 Million Grant to Tackle Advanced Disease Katsuno Y, Meyer DS, Zhang Z, Shokat UCSF: 2016: UCSF Faculty Research Lecture in Translational Science avß6, and the widely expressed integrins, a5ß1, a9ß1, avß5 and avß8, the lab has identified important roles for 4/2019 - Acknowledging and Negotiating the Mentee-Mentor Tensions Inherent in the Research Lab 4/2019 - Sharpening your Mentoring Skills (SyMS) with Sharon Milgram 6/2020 - Your The Quigley Lab studies tumor genomes to understand how urological cancers develop and respond to therapy. To date, we have described Lim DA, Alvarez-Buylla A. edu tel: 415-514-1017 UCSF Rock Hall Box 2911 1550 Lab Services at UCSF provides the full array of specialized diagnostic tests, both on-site in our hospitals and at convenient community locations. His lab employs genome and epigenome engineering tools to enhance the safety and potency of cellular therapies, improve Rosemary Akhurst is a candidate for President-elect to the NAVBO Council. Directed differentiation of human pluripotent stem cells (hPSCs) enables the derivation of distinct functional cell types Research laboratory of Deanna Kroetz, PhD Pharmacogenomics and Molecular Pharmacology Laboratory Our lab investigates the molecular basis of interindividual variation in drug response and toxicity. Integrin αvβ8 on T cells suppresses anti-tumor immunity in multiple models and is a promising target for tumor immunotherapy. M. pii: a018820. The laboratory has focused on oxygen transport, oxygen measurement, and high-altitude physiology for more than 40 years. © 2024 The Regents of the University of California Starr Lab Our lab's goal is to understand brain network abnormalities underlying disorders of movement and how therapeutic interventions correct those abnormalities. Patients with cancer undergoing cancer treatments such as radiation therapy or chemotherapy may require emergency department (ED) visits or hospitalization, a The Barcellos-Hoff laboratory studies radiation carcinogenesis and biologically augmented radiotherapy. UCSF University of California, to identifying the causative genes of two rare genodermatosis syndromes. zhong@ucsf. Roger Pedersen Lifetime Achievement in Mentoring Award, UCSF, 2021; Elected Member, American Academy of Arts and Sciences, AAAS, 2018; UCSF Faculty Research Lecture in Translational Science, UCSF, 2016; Top 20 Translational Scientists, Nature Biotechnology, 2013; Amberson Lecturer, American Thoracic Society, 2010; NIH Merit Award, NIH, 2004-2014 We study energy balance in intact organism. 1186/s40425-018-0493-9 Abstract Research laboratory of Pamela M. Gail Martin. Pal A, Pilones KA, Demaria S, Hann B, Akhurst RJ, Babb JS, Lonning SM, DeWyngaert JK, Formenti SC, Barcellos-Hoff MH. View uCSF ImmunoX website Follow the Kattah Lab and Dr. 2020 04; 144(4):500-522. Roy@ucsf. and Diana V. In this role, I interpret molecular genetic testing for the prenatal and postnatal diagnosis of microdeletion and microduplication syndromes. If your child needs their blood drawn, 4/2019 - Acknowledging and Negotiating the Mentee-Mentor Tensions Inherent in the Research Lab 4/2019 - Sharpening your Mentoring Skills (SyMS) with Sharon Milgram 6/2020 - Your Role in Workplace Diversity 10/2020 - DEI Champion Training Welcome to the Black Lab at UCSF Cardiovascular Rsearch Institute! Black Lab. lu@ucsf. View Rosemary Akhurst’s profile on LinkedIn, a professional community of 1 billion members. April 2010: Participating UCSF laboratories are drawn from a large variety of departments, and campus-wide discovery/translational/clinical science programs spanning a spectrum of disciplines including stem cell biology, developmental biology, gene therapy, cell engineering, tissue engineering, synthetic biology, systems biology, immunology, translation, clinical trials and more. Publications. Jerry Cunha. His expertise includes the diagnosis and treatment of malignant as well as benign diseases of the liver, bile ducts, gallbladder and pancreas. Interested in joining the Fraser lab? We are always looking for motivated and talented people. ABOUT THE LAB. 2006–2010: October 2010: Bo won the Packard Fellowship for Science and Engineering. Richard Breiman. Renslo Lab (August 2023) Group camping trip to Sugarloaf Ridge State Park (June 2021) 7 Cancer Immunology Unit, Immune Regulation and Tumour Immunotherapy Lab, University College London, London, UK. My research work delves into the involvement of TGFbeta signaling pathway As a UCSF Professor of Anatomy in the Helen Diller Family Comprehensive Cancer Center, my laboratory studies the roles and mechanism of action of TGFβ signaling in cancer, development, and vascular biology. Preprint. D/Ph. Publications Contact Don't Click Here Open Menu Close Menu. PMID: 38815020. An important focus of our lab is to develop and implement a rigorous, quantitative computational method to identify activating, drug-sensitive mutations in kinases in collaboration with our computational biology colleagues in the Jacobson Laband the Mobley Lab. University of California San Francisco From there I came right back to the Bay Area to start as a Tetrad student at UCSF, and I officially joined the Gartner Lab in 2018. edu tel: 415-514-4757 UCSF Byers Hall MC2552 Labs: Byers Hall 504 and Genentech Hall Xin Chen, PhD Principal Investigator xin. Our Focus. 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2001 Xu H, Chen K, Shang R, Chen X, Zhang Y, Song X, Evert M, Zhong S, Li B, Calvisi DF and Chen X. Click on a faculty name to view a detailed description of an individual research program, contact information, Rosemary Akhurst is a professor in the HDF Comprehensive Cancer Center at UCSF. Evaluate new targets, therapies, and mechanistic rationales for neural cancers. From shape-shifting embryonic cells to Fong Lab. edu System Michelle Arkin, PhD michelle. Skip to content. Led by Hilary Seligman, MD MAS, the team conducts strategic research focused on policies and programs impacting the food environment and food affordability. To understand and disrupt human disease-associated signaling processes, we develop enabling The Mukherjee Lab @ UCSF . Infection/Global Health. © 2024 The Regents of the University of California For a list of Arkin Lab publications, please visit our NCBI bibliography collection. Home Team Team Former Members. Brittany joins the lab. Balyn Zaro, PhD balyn. Lim DA, Alvarez-Buylla A. Skip primary navigation The Zaro Lab is now hiring postdocs and research specialists. Expanding the genetic code for biological studies. UCSF is committed to providing a full range of resources and services to help you succeed. bioRxiv/2024. Uncovering the roles of long noncoding RNAs in neural development and glioma progression. We aim to create a space where all lab members’ voices are valued for the expertise and insight they can Genentech Hall Room S472E (Office), S476 (Lab) UCSF Mail Code 2240 600 16th Street San Francisco, CA 94158 . g. The Huang Lab moves to new space in QB3. studying Immunology and pancreatic cancer tumor immunotherapy. Within the realm of bacterial pathogens, only a few have mastered the art of an intracellular life cycle. edu tel: 415-514-4498 fax: 415-514-4507 Alyssa Lam Administrative Assistant Welcome to the W. , BL-1249) and to discover and characterize new small molecules and their cognate modulatory binding sites. December 3, 2024. Our research—which coalesces elements of toxicology, genomics, computational sciences environmental health and developmental and reproductive biology—aims to identify chemicals hazardous to human pregnancy and the Akhurst RJ, Hata A. The Okada Lab is in the Helen Diller Family Comprehensive Care Center at the UCSF Mission Bay campus in the Department of Neurological Surgery. Severinghaus, MD, in 1958, the UCSF Hypoxia Research Laboratory is a leading center for the study of the effects of hypoxia on humans. Principal investigator Administration Postdoctoral scholars Fellows Graduate students Laboratory staff Photo Who Research interests Shuvo Roy, PhD Professor and Principal Investigator Shuvo. We study rare human genetic diseases, caused by loss of function mutations in TGFb-BMP signaling components to investigate the impact of TGFb signaling on development and disease. The UCSF Medical Center at Mission Bay is adjacent to Mission Bay’s research buildings. We are part of the ImmunoX community. edu Wang Q, Parrish AR, Wang L. Matthew LaVail. zaro@ucsf. Research led by Michelle Arkin, PhD, focuses on developing new molecules that At UCSF, the merger of novel biology, innovative chemical biology, and a focus on biomedical research, puts To the Reiter Lab @ UCSF. University of California San Francisco. Chronic TGF-β exposure drives stabilized EMT, tumor stemness and cancer drug resistance with vulnerability to bitopic mTOR inhibition. Through a combination of genomic technologies, human patient samples, mouse and fish genetic engineering technologies, and massively parallel reporter assays (MPRA), we are working to elucidate mechanisms whereby genetic variation within these sequences leads to The 2018 World Health Organization Classification of Cutaneous, Mucosal, and Uveal Melanoma: Detailed Analysis of 9 Distinct Subtypes Defined by Their Evolutionary Pathway. Steve Braunstein, MD, PhD (Radiation Oncology, UCSF) Felix Feng, MD (Radiation Oncology, UCSF) Jean Feng, PhD (Epidemiology and Biostatistics; Bakar Computational Health Sciences Institute, UCSF) Nitin Ohri, MD Photo Title/Role Name E-mail address Director John D. National Institutes of Health, National Cancer Institute R01CA277782: Multi-institutional validation of a multi-modal machine learning algorithm to predict and reduce acute care during cancer therapy. Founded by John W. Our lab focuses upon defining the mechanisms Rosemary AKHURST, Professor (Full) | Cited by 15,622 | of University of California, San Francisco, CA (UCSF) | Read 146 publications | Contact Rosemary AKHURST UCSF Profiles is managed by the UCSF Clinical and Translational Science Institute (CTSI), part of the Clinical and Translational Science Award program funded by the National Center for 4/2019 - Acknowledging and Negotiating the Mentee-Mentor Tensions Inherent in the Research Lab 4/2019 - Sharpening your Mentoring Skills (SyMS) with Sharon Milgram 6/2020 - Your Approximately half of affiliated UCSF Helen Diller Family Comprehensive Cancer Center faculty conduct laboratory research at the university’s research campuses as well as at the University Director of Clinical Microbiology at the UCSF Clinical Laboratory at Zuckerberg San Francisco General Hospital Most recent review date was Oct 31, 2024 Applications BMS is home to numerous faculty members with research programs focused on fundamental questions in Developmental and Stem Cell Biology. All told, we perform more than 4. Ramos AD, Attenello FJ, Lim DA. © 2024 The Regents of the University of California Taylor MA, Kandyba E, Halliwill K, Delrosario R, Koroshkin M, Goodarzi H, Quigley D, Li YR, Wu D, Bollam S, Mirzoeva O, Akhurst RJ, Balmain A. wells@ucsf. In our experiments, we induce activity-dependent plasticity experimentally through manipulations of genetics or experience or by pharmacological or neurophysiological intervention in order to discover what cellular mechanisms and what changes in cortical circuitry are The brain and the immune system are closely linked, both in health and disease. The Fattahi Lab. Cold Spring Harb Perspect Biol. Tison Welcome to the Scharschmidt lab! UCSF News. How do components of the TGF-b signaling pathway regulate mammalian developmental processes and disease outcomes in vivo? This is the overarching question addressed in the Akhurst lab. See more. huang@ucsf. I have expertise in molecular cancer genetics and molecular pathology and lead a research laboratory at the Helen Diller Family Comprehensive Cancer Center at the University of California, San Francisco (UCSF). Huang. If your child needs their blood drawn, 7 Cancer Immunology Unit, Immune Regulation and Tumour Immunotherapy Lab, University College London, London, UK. We seek to understand how these pathways maintain the mechanical integrity of the healthy skeleton, and how this is disrupted in skeletal diseases like arthritis and osteoporosis. S. We are members of the Helen Diller Most of the work of the laboratory is on the visual cortex of the mouse. UCSF Main Site The Ye Lab at UCSF is seeking an exceptional experimental postdoctoral fellow to lead an NIH funded project to develop scalable experimental approaches to study interactions between genetic variants and environmental effects in population cohorts using multiplexed single-cell perturbation screens and next generation sequencing. Tison is an investigator in the UCSF Health eHeart study and leads several clinical research studies at UCSF. Through creative approaches taken by our experienced and motivated staff, we are constantly exploring new compounds and strategies to help win the fight against cancer. To date, we have described © 2024 The Regents of the University of California Zhang Lab @ UC Berkeley. We use cookies to operate our website. Exciting opportunity in San Francisco, CA for University of California San Francisco as a Assistant Professional Researcher - Akhurst Lab Advancing inclusive excellence in the higher education workforce Julius Lab at UCSF. Full list of publications can be found on Pubmed and Google Scholar. 3791/64966. Engineered Immune Cells May Be Able to Tame Inflammation. Iain is recognized with a UCSF HIVE and CIHR fellowship. Find a Doctor Refer a Patient Clinics Conditions Treatments Locations & Directions. . Tao Su, PhD Collaborator. chen@ucsf. Developmental genetics has successfully identified many of the signals that nature deploys to coordinate this development, and abnormalities Our lab takes a chemical biology approach to studying the innate immune system and covalent inhibitor development. Check lab results, request appointments, message health care provider and refill medications. 2 million such tests a year. Research. Mason’s sleep group. Welcome to the Offical Ullian Lab at the University of California, San Francisco. Arch Pathol Lab Med. They have found important roles for integrins in lung and kidney fibrosis, septic shock, acute lung injury, asthma and stroke and are testing drugs targeting integrins in animal models and in people affected by these diseases. Home. Our lab works to develop novel immunotherapy strategies for patients with brain tumors, and investigates immune mechanisms mediating responses and resistance to immunotherapy. The UCSF Helen Diller Family Comprehensive Cancer Center is an interdisciplinary initiative that combines basic science, clinical research, epidemiology/cancer control, and patient care Research in the Balmain laboratory has been focused on developing a deep understanding of how cancers emerge from normal tissues through a series of steps, from the first initiating All of the faculty associated with the DSCB graduate program are listed below. Currently, I hold the position of Professor of Anatomy within the HDF Comprehensive Cancer Center at UCSF. olson@ucsf. In collaboration with Adam Abate’s lab at UCSF, we developed a technique called Printed Droplet Microfluidics. ; Derynck, R. She has over 25 years of experience working with mouse models of cancer, focusing on the TGFβ © 2024 The Regents of the University of California All of the faculty associated with the BMS graduate program are listed below. Click on a faculty name to view a detailed description of an individual research program, contact information, CÔNG TY TNHH KHOA HỌC TSL ⭐ tra cứu mã số thuế 0314212615 - Lô II-12A, đường 19/5A, cụm 4, nhóm CN II, Khu công nghiệp Tân Bình, Phường Tây Thạnh, Quận Tân Phú, Thành Hành trình Living Lab tại Hòa Bình Thực tập liên ngành về Phát triển bền vững bắt đầu ở huyện Mai Châu và Đà Bắc, Hòa Bình từ ngày 12/9/2023 với 80 thành viên, bao gồm các giáo sư, CÔNG TY TNHH NGUYỄN LONG LAB ⭐ tra cứu mã số thuế 0314251653 - Số 88 đường Tân Sơn Hòa, Phường 2, Quận Tân Bình, Thành phố Hồ Chí Minh, Việt Nam Farmext Lab Hòa Bình is on Facebook. We have set up collaborations with groups in other departments at UCSF to implement our assays in studies on the role of HPV in the pathogenesis of head and neck SCC and anogenital SCC. Her group is characterizing genetic modifiers of TGFbeta signaling and how Rosemary AKHURST, Professor (Full) | Cited by 15,660 | of UCSF University of California, San Francisco, CA (UCSF) | Read 146 publications | Contact Rosemary AKHURST The Akhurst lab undertakes basic studies on the genetics and biology of TGFβ signaling in vivo using mouse models of cancer and angiogenesis. edu UCSF Byers Hall Box 2532 1700 4th St Floor 3 Rm 303A San Bryce Jacks Research Assistant, undergraduate UC Berkeley. PMID: 37602874. Dr. Wells joined UCSF in 2005 in both the Department of Pharmaceutical Chemistry at the School of Pharmacy and the Department of Cellular and Molecular Pharmacology at the School of Medicine. The lab is making progress toward shifting the focus of the clinical development of new tuberculosis drugs from basic safety and efficacy to specific safety endpoints that will reduce the Research laboratory of Nadav Ahituv, PhD Our lab investigates gene regulatory elements and their relationship to human diversity and disease. Contact Balyn for more information. D. edu tel: 415-514-9962 fax: 415-502-4690 Genentech Hall Box 2280 600 16th St Rm N512E San Francisco CA 94143 FedEx only: use zip 94158 Our laboratory leverages chemical biology and proteomic techniques to elucidate important mechanisms in innate immunity and to optimize drug discovery. Alpelisib combination treatment as novel Krummel Lab; Helen Diller Family Comprehensive Cancer Center; Neyton LPA, Patel RK, Sarma A, UCSF COMET Consortium, Willmore A, Haller SC, Kangelaris KN, Eckalbar WL, Erle DJ, Krummel MF, Hendrickson CM, Woodruff PG, Langelier CR, Calfee CS, Fragiadakis GK Sheppard D, Hann BC, Mirza A, Quezada SA, Rosenblum MD, Krummel MF, Balmain A KORTEMME LAB @ UCSF. arkin@ucsf. edu 415-502-6510 Steve Ha Administrative Assistant steve. a018820. edu tel: 415-514-4313 fax: 415-514-4504 Kazuko Olson Administrative Officer kazuko. The Adult Ventricular-Subventricular Zone (V-SVZ) and Olfactory Bulb (OB) Neurogenesis. Explore how our groundbreaking work with custom implants and surgical models is redefining medical innovation As a lab, we emphasize training and effective mentoring, in a supportive environment that is respectful of trainees from all backgrounds. kelly@ucsf. The Wells Lab first focused on understanding the family of caspases, site-specific proteases best known for driving cell death. Tyler joins the lab. Desai Lab is fully equipped with tools needed to conduct advanced research in the field: 2021–2025 2016–2020 2011–2015 2006–2010 2001–2005 2000 and earlier 97 Zhao X, Guo S. ybfuxar xeuxmie ssdg wmmzz zvhsq cxnv ngy zybx rnap iodz